Contribution of Salmonella gallinarum large plasmid toward virulence in fowl typhoid
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چکیده
منابع مشابه
Contribution of Salmonella gallinarum large plasmid toward virulence in fowl typhoid.
Four strains of Salmonella gallinarum isolated from independent cases of fowl typhoid all possessed both an 85-kilobase and a 2.5-kilobase plasmid. Each plasmid was eliminated in turn from one of the strains by transposon labeling and curing at 42 degrees C. Elimination of the small plasmid had no effect on the high virulence of the strain for newly hatched and 2-week-old chickens. Whereas oral...
متن کاملReproduction of fowl typhoid by respiratory challenge with Salmonella Gallinarum.
Fowl typhoid is a disease of adult chickens and is caused by Salmonella Gallinarum infection via the alimentary tract. The experimental reproduction of fowl typhoid per os (PO) requires artificial conditions to minimize the effect of gastric acid, and several Salmonella serovars have been known to be transmitted via the respiratory route. Therefore, we have hypothesized the existence of a respi...
متن کاملComparison of immune responses of two Salmonella gallinarum strains viewed as possible vaccines for fowl typhoid in Kenya.
The immune responses of two S. gallinarum strains, L46 and CN 180, were compared in 15-week-old cockerels. The humoral and cell-mediated immune responses were assayed by means of the indirect haemagglutination test (IHA) and the macrophage migration inhibition test (MIT), respectively. Birds were vaccinated with the two vaccines, respectively, and bled for sera (for IHA) and cells (for MIT) eve...
متن کاملEvaluation of protective efficacy of live attenuated Salmonella enterica serovar Gallinarum vaccine strains against fowl typhoid in chickens.
Salmonella enterica serovar Gallinarum is the etiological agent of fowl typhoid, which constitutes a considerable economic problem for poultry growers in developing countries. The vaccination of chickens seems to be the most effective strategy to control the disease in those areas. We constructed S. Gallinarum strains with a deletion of the global regulatory gene fur and evaluated their virulen...
متن کاملPhysiology, pathogenicity and immunogenicity of lon and/or cpxR deleted mutants of Salmonella Gallinarum as vaccine candidates for fowl typhoid
To construct a novel live vaccine candidate for fowl typhoid (FT) caused by Salmonella Gallinarum (SG), the lon and cpxR genes that are related to host-pathogen interaction were deleted from a wild type SG using the allelic exchange method. The mutants were grown normally, as was the wild type. The biochemical properties of the mutants remained very similar to those of the wild-type, while JOL9...
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ژورنال
عنوان ژورنال: Infection and Immunity
سال: 1987
ISSN: 0019-9567,1098-5522
DOI: 10.1128/iai.55.2.388-392.1987